github link
Accession IconGSE35244

Gene expression analysis of a human thymic cell line model of AIRE molecular function

Organism Icon Homo sapiens
Sample Icon 4 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description
Microarray analysis of AIRE regulated gene expression has been performed extensively in studies using the thymi of different mouse strains, but to date, has only been rarely performed using human model systems, and critically, not yet with a human thymic model. We have generated a Flp-In host cell line variant of the TEC 1A3 human thymic epithelial cell line and subsequently used site-specific recombination to generate a variant that stably expresses recombinant AIRE. We used microarray analysis to determine the transcription expression profiles of these two variants and determine the repertoire of AIRE regulated gene expression in a human thymic model system.
PubMed ID
No associated PubMed ID
Publication Title
No associated publication
Total Samples
6
Submitter’s Institution
Authors
No associated authors
Alternate Accession IDs

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Cell line
Processing Information
Additional Metadata
No rows found
Loading...