Sex differences during acute myocarditis against coxsackievirus B3 (CVB3)-induced myocarditis (10 dpi) and chronic myocarditis/dilated cardiomyopathy (DCM) against CVB3-induced myocarditis (90 dpi)

GSE35182

Mus musculus

24 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

Men are at an increased risk of dying from heart failure caused by inflammatory heart diseases such as atherosclerosis, myocarditis and dilated cardiomyopathy (DCM). We previously showed that immune responses in the heart are phenotypically distinct in male compared to female mice 10 days after infection resulting in severe DCM in males.

PubMed ID

22328081

Publication Title

Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n.

Total Samples

Submitter’s Institution

Johns Hopkins University

Authors

Coronado MJ, Brandt JE, Kim E, Bucek A, Bedja D, Abston ED, Shin J, Gabrielson KL, Mitzner W, Fairweather D

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-35182

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