Identification of LEDGF-regulated genes.

GSE3485

Homo sapiens

No Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

The LEDGF transcript from the PSIP1 gene was knocked down using RNAi technology. The resulting 293T derived cell line (293TsiLL) was compared to a control cell line (293TsiScram) using microarray analysis. Genes identified as being modulated by LEDGF were preferential targets of HIV integration.

PubMed ID

16311605

Publication Title

A role for LEDGF/p75 in targeting HIV DNA integration.

Total Samples

Submitter’s Institution

University of Pennsylvania

Authors

Ciuffi A, Llano M, Poeschla E, Hoffmann C, Leipzig J, Shinn P, Ecker JR, Bushman F

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-3485

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