Expression data from the dorsal root ganglia during streptozotocin-induced painful diabetic neuropathy in rats

FK1706 potentiated nerve growth factor-induced neurite outgrowth, putatively mediated via FKBP-52 and the Ras/Raf/MAPK signaling pathway. It also improved mechanical allodynia accompanied by the recovery of intraepidermal nerve fiber density in a painful diabetic neuropathy in rats.

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Yamazaki S, Yamaji T, Murai N, Yamamoto H, Matsuda T, Price RD, Matsuoka N