The effect of androgen deprivation on human prostate xenograft tumor LuCaP35

GSE33316

Homo sapiens

9 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Androgen deprivation is a standard of care front-line therapy for human prostate cancer, however, majority of patients will eventally develop resistance to androgen deprivation. In this study, using a human prostate cancer xenograft model -LuCaP35, we examiend the gene expression changes after castration.

PubMed ID

22108827

Publication Title

Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy.

Total Samples

Submitter’s Institution

Genentech

Authors

Sun Y, Wang BE, Leong KG, Yue P, Li L, Jhunjhunwala S, Chen D, Seo K, Modrusan Z, Gao WQ, Settleman J, Johnson L

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-33316

No rows found