Targeted disruption of the BCL9/beta-catenin complex in cancer

GSE33143

Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Stabilized Alpha-Helix peptides of BCL9 HD2 (SAH-BCL9) block BCL9 and B9L interactions with beta-catenin and specifically downregulate Wnt target gene expression.

PubMed ID

22914623

Publication Title

Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling.

Total Samples

Submitter’s Institution

Bioinfo

Authors

Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-33143

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