Study of Mid-Blastula Transition of zebrafish embryos

GSE32914

Danio rerio

10 Downloadable Samples

Affymetrix Zebrafish Genome Array (zebrafish)

Submitter Supplied Information

Description

Sox31 is a member of the zebrafish SoxB1 subfamily, and its expression can be detected both pre- and post-MBT. To distinguish the function of its maternal and zygotic transcripts, a splice blocking morpholino (Sb MO) was designed to interfere with the processing of new, zygotically synthesised mRNAs without interfering with mRNAs of maternal origin. Developmental arrest was observed in Sb MO which could not bypass MBT.

PubMed ID

22209980

Publication Title

Splice blocking of zygotic sox31 leads to developmental arrest shortly after Mid-Blastula Transition and induces apoptosis in zebrafish.

Total Samples

Submitter’s Institution

Shanghai Center for Bioinformation Technology

Authors

Hu SN, Yu H, Zhang YB, Wu ZL, Yan YC, Li YX, Li YY, Li YP

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-32914

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