Whole Genome Expression after Hypoxia and Reoxygenation in the Newborn Mouse Lung, Brain and Eye

GSE32500

Mus musculus

177 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

Perinatal asphyxia is detrimental to the newborn baby and the use of supplemental oxygen during resuscitation may worsen the prognosis of these babies. The mechanism behind hyperoxic injury is not fully understood and our aim was to investigate four oxygen therapies following hypoxia and these effects on transcriptional activity.

PubMed ID

24375083

Publication Title

Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes.

Total Samples

177

Submitter’s Institution

University of Oslo

Authors

Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, Nygård S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-32500

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