MX1 is Silenced in Permissive HRP4 Cells Supporting HCV Replication

MX1 is a well-characterized interferon-induced antiviral gene. MX1 is activated by viral infection due to interferon production in cells. We treated non-permissive Huh7 cells and permissive HRP4 cells with interferon. We compared the expression of genes induced by interferon to determine host factors affecting HCV replication.

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Chen Q, Denard B, Huang H, Ye J