Expression data of Dnmt1 haploinsufficient leukemia stem cells and bulk leukemia

Leukemia stem cells (LSCs) are an attractive target in treatment of many types of blood cancers. There remains an incomplete understanding of the epigenetic mechanisms driving LSC formation and maintenance, and how this compares to the epigenetic regulation of normal hematopoietic stem cells (HSCs).

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Trowbridge JJ, Sinha AU, Zhu N, Li M, Armstrong SA, Orkin SH