Effects of benfotiamine in cultured human myotubes exposed to both normal and high glucose cencentrations

GSE31553

Homo sapiens

8 Downloadable Samples

Illumina HumanWG-6 v3.0 expression beadchip

Submitter Supplied Information

Description

The aim of the present work was to study the effects of benfotiamine (S-benzoylthiamine O-monophosphate) upon glucose and lipid metabolism and gene expression in differentiated human skeletal muscle cells (myotubes) incubated for 4 days under normal (5.5 mM glucose) and hyperglycemic (20 mM glucose) conditions.

PubMed ID

21984258

Publication Title

Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations.

Total Samples

Submitter’s Institution

University of Oslo

Authors

Fraser DA, Hessvik NP, Nikolić N, Aas V, Hanssen KF, Bøhn SK, Thoresen GH, Rustan AC

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-31553

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