Genome-wide Expression Assay Comparison Across Frozen and Fixed Postmortem Brain Tissue Samples

GSE28475

Homo sapiens

143 Downloadable Samples

Illumina HumanRef-8 v3.0 expression beadchip

Submitter Supplied Information

Description

Comparison between in vitro transcription- and cDNA-mediated annealing, selection and ligation (DASL)-based assays on brain-specific reference RNA, and postmortem frozen and formalin fixed brain tissue from autistic and control cases. Investigation of data preprocessing techniques for DASL-assayed RNA samples from frozen brain tissue.

PubMed ID

22375143

Publication Title

Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples.

Total Samples

143

Submitter’s Institution

NIH-UC San Diego Autism Center of Excellence

Authors

Chow ML, Winn ME, Li HR, April C, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-28475

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