Gene expression data for the budding yeast mutants pol30-8, dot1 and pol30-8 dot1

The mutation in the budding yeast gene PCNA, pol30-8, as well as deletion of DOT1 (dot1), encoding the only histone H3 K79 methyltransferase in budding yeast, have been implicated in telomeric silencing. To further analyze these mutants, we used microarrays to study whether either pol30-8, dot1 or the double mutant leads to changes in gene expression levels when compared to isogenic wild-type strains.

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Rossmann MP, Luo W, Tsaponina O, Chabes A, Stillman B