mRNAs associated with human Pumilio2 protein (PUM2)

The presence of the PUF (Pumilio/FBF) domain defines a conserved family of RNA-binding proteins involved in repressing gene expression. It has been suggested that a conserved function of PUF proteins is to repress differentiation and sustain the mitotic proliferation of stem cells. In humans, Pumilio2 (PUM2) is expressed in embryonic stem cells and adult germ cells.

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Shigunov P, Sotelo-Silveira J, Kuligovski C, de Aguiar AM, Rebelatto CK, Moutinho JA, Brofman PS, Krieger MA, Goldenberg S, Munroe D, Correa A, Dallagiovanna B