Expression data from human amnion mesenchymal cells treated with interleukin-1-beta for 1hr and 8hr

GSE26315

Homo sapiens

9 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

Premature birth continues to be a challenging pregnancy complication, and a body of literature indicates that inflammation can contribute to premature delivery by converting a receptive uterine environment to a hostile one. Cytokines have been demonstrated to provoke up-regulation of inflammatory genes (e.g. interleukin-1, 6, and 8, tumor necrosis factor-alpha, cyclooxygenase-2, and microsomal prostaglandin E synthase-1).

PubMed ID

21655103

Publication Title

Inflammatory gene regulatory networks in amnion cells following cytokine stimulation: translational systems approach to modeling human parturition.

Total Samples

Submitter’s Institution

The Ohio State University

Authors

Li R, Ackerman WE 4th, Summerfield TL, Yu L, Gulati P, Zhang J, Huang K, Romero R, Kniss DA

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-26315

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