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Accession IconGSE25198

RNA profiles of embryonic stem cells generated from in vitro produced or in vivo derived rhesus preimplantation embryos

Organism Icon Macaca mulatta
Sample Icon 8 Downloadable Samples
Technology Badge Icon Affymetrix Rhesus Macaque Genome Array (rhesus)

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It is often overlooked that human ESCs are generated from in vitro cultured, often surplus/discard, embryos considered unsuitable for transfer in infertility clinics. In vitro culture of preimplantation embryos has been associated with a number of perturbations, including ultrastructure, gene expression, metabolism and post-transfer development. We report here the transcriptional profiles characteristic of ESC lines generated from either in vitro cultured or in vivo derived embryos.
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