Genome-wide analysis of the effect of cryopreservation on peripheral blood mononuclear cells

GSE24753

Homo sapiens

24 Downloadable Samples

Illumina human-6 v2.0 expression beadchip

Submitter Supplied Information

Description

Analysis of cryopreservation effects on peripheral blood mononuclear cells at gene expression level. The hypothesis tested in the present study was that cryopreservation has an influence on the transcriptome profile of peripheral blood mononuclear cells. Results indicated remarkable changes in expression patterns upon cryopreservation of PBMCs, with a strong loss of signal intensities to background levels for several transcripts.

PubMed ID

21704280

Publication Title

RNA-stabilized whole blood samples but not peripheral blood mononuclear cells can be stored for prolonged time periods prior to transcriptome analysis.

Total Samples

Submitter’s Institution

University of Bonn

Authors

Debey-Pascher S, Hofmann A, Kreusch F, Schuler G, Schuler-Thurner B, Schultze JL, Staratschek-Jox A

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-24753

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