Effect of TIF1 gene deletion on hematopoietic stem cells

GSE22280

Mus musculus

2 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Analysis of KLS cells purified from bone marrow of mice conditionally inactivated for TIF1 gene. TIF1 deletion results in multiple defects in adult hematopoiesis. Results provide insight into the role of TIF1 in hematopoietic stem cells functions.

PubMed ID

21474105

Publication Title

Adult hematopoiesis is regulated by TIF1γ, a repressor of TAL1 and PU.1 transcriptional activity.

Total Samples

Submitter’s Institution

IGBMC

Authors

Kusy S, Gault N, Ferri F, Lewandowski D, Barroca V, Jaracz-Ros A, Losson R, Romeo PH

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-22280

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