Expression data from mesothelial (LP9) and mesothelioma cells (HMESO) inhibited for extracellular-regulated kinase (ERK) 1, 2, or 5

GSE21750

Homo sapiens

18 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

Extracellular-regulated kinases (ERK1/2 and 5) are known to play important roles in growth and drug resistance of various cancers. Here we show roles of inhibition of ERK1, ERK2, or ERK5 on gene expression profiles of epithelioid malignant mesothelioma (MM) cells (HMESO).

PubMed ID

21159167

Publication Title

Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin.

Total Samples

Submitter’s Institution

University of Vermont

Authors

Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Pass HI, Carbone M, Testa JR, Mossman BT

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-21750

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