Maternal influences on the transmission of leukocyte gene expression profiles in population samples (mother and child)

This study contrasts the expression profiles of peripheral blood leukocytes from third trimester pregnant mothers, with cord blood leukocytes from their newborn children. It is a companion to (GSE21311). After normalization for RNA integrity, major principal components of the variation were found to distinguish individuals. Transmission of gene expression profiles from mother to child was documented, along with differences between gestational diabetic, obese, and normal weight mothers and their children.

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Mason E, Tronc G, Nones K, Matigian N, Kim J, Aronow BJ, Wolfinger RD, Wells C, Gibson G