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Accession IconGSE21231

Gene expression changes associated with resistance to intravenous corticosteroid therapy in children with severe ulcerative colitis

Organism Icon Homo sapiens
Sample Icon 40 Downloadable Samples
Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

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Description
Although corticosteroids remain a mainstay of therapy for UC, a meta-regression of cohort studies in acute severe ulcerative colitis (UC) showed that 29% of patients fail corticosteroid therapy and require escalation of medical management or colectomy.
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40
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