VCAM1 promotes outbreak from dormant bone metastasis

GSE20611

Homo sapiens

11 Downloadable Samples

Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

A weakly bone metastatic variant of the breast cancer cell line MDA-MB-231, SCP6, gave rise to highly bone metastatic sublines (PD1, PD2A-E) after long time dormancy in vivo. These cell lines were subjected to microarray analysis with data drawn from previous studies (Kang et al., 2003; Minn et al. 2005; Lu and Kang 2009; Lu and Kang 2010).

PubMed ID

22137794

Publication Title

VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors.

Total Samples

Submitter’s Institution

Princeton University

Authors

Lu X, Mu E, Wei Y, Riethdorf S, Yang Q, Yuan M, Yan J, Hua Y, Tiede BJ, Lu X, Haffty BG, Pantel K, Massagué J, Kang Y

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-20611

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