Expression data of multiple sclerosis patients receiving intramuscular Interferon-beta-1a therapy [U133 A and B]

GSE19285

Homo sapiens

137 Downloadable Samples

Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

The purpose of this study was to characterize the transcriptional effects induced by intramuscular IFN-beta-1a treatment (Avonex, 30 g once weekly) in patients with relapsing-remitting form of multiple sclerosis (MS). By using Affymetrix DNA microarrays, we obtained genome-wide expression profiles of peripheral blood mononuclear cells from 24 MS patients within the first four weeks of IFN-beta administration.

PubMed ID

20956993

Publication Title

Network analysis of transcriptional regulation in response to intramuscular interferon-β-1a multiple sclerosis treatment.

Total Samples

144

Submitter’s Institution

University of Rostock

Authors

Hecker M, Goertsches RH, Fatum C, Koczan D, Thiesen HJ, Guthke R, Zettl UK

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-19285

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