New candidate gene identification for controlling mammalian gonadal sex determination

GSE18211

Mus musculus

11 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Mammalian gonadal sex determination is dependent on proper expression of sex determining genes in fetal gonadal somatic support cells (i.e., pre-granulosa and pre-Sertoli cells in XX and XY gonads, resp.). We used a unique transgenic mouse strain combined with microarray profiling to identify all the differentially expressed transcripts in XX and XY isolated somatic support cells during critical stages of gonadal development and differentiation.

PubMed ID

19864314

Publication Title

New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation.

Total Samples

Submitter’s Institution

Colorado State University

Authors

Bouma GJ, Hudson QJ, Washburn LL, Eicher EM

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-18211

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