Gene expression profiling of mesenchyme-derived cell populations in the human airways

Mesenchyme-derived cells in the human airway wall including airway smooth muscle cells, fibroblasts and myofibroblasts are known to play important roles in airway remodeling. The lack of specific phenotypic markers makes it difficult to define these cell populations in primary cultures. The objectives of this study were to evaluate reported markers and to identify novel markers to define these cell types.

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Singh SR, Billington CK, Sayers I, Hall IP