Sex-related transcriptional differences in Day 7 bovine in vitro produced blastocysts

Sexual dimorphism in mammals is mostly attributable to sex-related hormonal differences in fetal and adult tissues; however, this may not be the sole determinant. Though genetically-identical for autosomal chromosomes, male and female preimplantation embryos could display sex-specific transcriptional regulation which can only be attributted to the differences in sexual chromosome dosage.

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Bermejo-Alvarez P, Rizos D, Rath D, Lonergan P, Gutierrez-Adan A