Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria

GSE17840

Mus musculus

9 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Epithelial Hedgehog (Hh) ligands regulate several aspects of fetal intestinal organogenesis and emerging data implicate the Hh pathway in inflammatory signaling in adult colon. We investigated the effects of chronic Hh inhibition in vivo and profiled molecular pathways acutely modulated by Hh signaling in the intestinal mesenchyme.

PubMed ID

20206176

Publication Title

Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria.

Total Samples

Submitter’s Institution

University of Michigan Medical School

Authors

Zacharias WJ, Li X, Madison BB, Kretovich K, Kao JY, Merchant JL, Gumucio DL

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-17840

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