Molecular Classification of AIDS-Related Lymphomas

GSE17189

Homo sapiens

11 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Gene expression profiling (GEP) of ARL patient samples was done to determine whether gene expression signatures derived from HIV- lymphomas retained their ability to molecularly classify HIV+ lymphomas. The GEP-based predictors robustly classified ARL tumors, distinguishing molecular Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL), as well as activated B-cell-like (ABC) and germinal center B-cell-like (GCB) molecular subtypes of DLBCL.

PubMed ID

20216076

Publication Title

Recurrent chromosomal alterations in molecularly classified AIDS-related lymphomas: an integrated analysis of DNA copy number and gene expression.

Total Samples

Submitter’s Institution

University of Nebraska Medical Center

Authors

Deffenbacher KE, Iqbal J, Liu Z, Fu K, Chan WC

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-17189

No rows found