Hepatic gene expression before and during interferon and ribavirin combination therapy

Patients who cleared HCV viremia early during therapy tended to show favorable outcomes, whereas patients who needed a longer period to clear HCV had poorer outcomes. We explored the mechanisms of treatment resistance by comparing hepatic gene expression before and during treatment

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Honda M, Nakamura M, Tateno M, Sakai A, Shimakami T, Shirasaki T, Yamashita T, Arai K, Yamashita T, Sakai Y, Kaneko S