Determining direct targets of the bHLH MIST1

GSE16924

Homo sapiens

5 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

The transcription factor MIST1 is required for final maturation of secretory cells of diverse tissues, including gastric digestive-enzyme secreting zymogenic (chief) cells (ZCs). Here, we show that MIST1 directly activates RAB26, RAB3D and several other genes.

PubMed ID

20038531

Publication Title

RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation.

Total Samples

Submitter’s Institution

Washington University

Authors

Tian X, Jin RU, Bredemeyer AJ, Oates EJ, Błazewska KM, McKenna CE, Mills JC

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-16924

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