Expression data from MDA-MB-231 reference and in vitro-derived subpopulations with distinct invasive potentials

To understand the link between invasion behavior and the steps of metastasis formation, we isolated invasive subpopulations from MDA-MB-231 cells in vitro using matrigel coated boyden chambers. Whole genome transcriptional profiling was used to characterize the expression changes uniquely related to invasive abilities of these cells.

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Abdelkarim M, Vintonenko N, Starzec A, Robles A, Aubert J, Martin ML, Mourah S, Podgorniak MP, Rodrigues-Ferreira S, Nahmias C, Couraud PO, Doliger C, Sainte-Catherine O, Peyri N, Chen L, Mariau J, Etienne M, Perret GY, Crepin M, Poyet JL, Khatib AM, Di Benedetto M