Transcriptional changes in the absence of nth-1, xpa-1 and nth-1;xpa-1

GSE16405

Caenorhabditis elegans

9 Downloadable Samples

Affymetrix C. elegans Genome Array (celegans)

Submitter Supplied Information

Description

Background: The ability of an organism to repair damages to DNA is inextricably linked to aging and cancer. We have characterized and compared the transcriptome of C. elegans mutants deficient in DNA base excision repair, nucleotide excision repair or both to elucidate the transcriptional changes incurred by the reduction of these repair pathways.

PubMed ID

20382984

Publication Title

A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.

Total Samples

Submitter’s Institution

University of Oslo

Authors

Fensgård Ø, Kassahun H, Bombik I, Rognes T, Lindvall JM, Nilsen H

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-16405

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