Time course of 1,25(OH)2D treated RWPE1 cells.

GSE15947

Homo sapiens

24 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Background: Prostate cancer is the second leading cause of cancer mortality among US men. Epidemiological evidence suggests that high vitamin D status protects men from prostate cancer and the active form of vitamin D, 1,25 dihydroxyvitamin D3 (1,25(OH)2D) has anti-cancer effects in cultured prostate cells. Still, the molecular mechanisms and the gene targets for vitamin D-mediated prostate cancer prevention are unknown.

PubMed ID

20070897

Publication Title

1,25 dihydroxyvitamin D-mediated orchestration of anticancer, transcript-level effects in the immortalized, non-transformed prostate epithelial cell line, RWPE1.

Total Samples

Submitter’s Institution

Purdue University

Authors

Kovalenko PL, Zhang Z, Cui M, Clinton SK, Fleet JC

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-15947

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