Expression data for conditional Dnmt1knockout hematopoietic stem and progenitor cells

GSE15840

Mus musculus

14 Downloadable Samples

Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Submitter Supplied Information

Description

DNA methylation is essential for mammalian development and plays crucial roles in a variety of biological processes. The DNA methyltransferase Dnmt1 serves to maintain parental cell methylation patterns on daughter DNA strands in mitotic cells, however, the precise role of Dnmt1 in regulation of quiescent adult stem cells is not known.

PubMed ID

19796624

Publication Title

DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells.

Total Samples

Submitter’s Institution

Dana-Farber Cancer Institute

Authors

Trowbridge JJ, Snow JW, Kim J, Orkin SH

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-15840

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