High-fat diet leads to tissue-specific changes reflecting risk factors for diseases in DBA/2J mice

Analysis of tissues of DBA/2 mice fed a standard breeding diet (SBD) and high fat diet (HFD) revealed tissue specific roles in inflammation and disease, and altered communication between tissues. The tissues surveyed incuded adipose tissues (brown, inguinal, mesenteric, retro-peritoneal, subcutaneious and gonadal), muscle and liver.

96

Hageman RS, Wagener A, Hantschel C, Svenson KL, Churchill GA, Brockmann GA