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Accession IconGSE155640

Expression data from THP1-wt and THP1-NTR+ cells with LSD1 inhibitor (OG86), Nitroreductase NfsB (NTR) prodrug and negative control

Organism Icon Homo sapiens
Sample Icon 42 Downloadable Samples
Technology Badge Icon Affymetrix Clariom S Human array (clariomshuman)

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Description
The Nitroreductase NfsB (NTR) prodrug of an LSD1 inhibitor is inactive in wild-type THP1 cells, but the prodrug gets activated in the LSD1 inhibitor by the NTR in NTR-expressing THP1 cells (THP1-NTR+).
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