Gene expression profiles of mono- and biallelic CEBPA mutations in cytogenetically normal AML

GSE15210

Homo sapiens

61 Downloadable Samples

Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

Purpose: CEBPA mutations are found as either biallelic (biCEBPA) or monoallelic (moCEBPA). We set out to explore whether the kind of CEBPA mutation is of prognostic relevance in cytogenetically normal AML (CN-AML).

PubMed ID

20038735

Publication Title

Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.

Total Samples

Submitter’s Institution

University of Munich

Authors

Dufour A, Schneider F, Metzeler KH, Hoster E, Schneider S, Zellmeier E, Benthaus T, Sauerland MC, Berdel WE, Büchner T, Wörmann B, Braess J, Hiddemann W, Bohlander SK, Spiekermann K

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-15210

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