Lacrimal gland myoepithelial cells are altered in a mouse model of dry eye disease

The purpose of this study was to determine the pathogenic changes that occur in myoepithelial cells (MECs) from lacrimal glands of a mouse model of Sjogren’s syndrome. MECs were cultured from lacrimal glands of C57BL/6J (wild type, WT), and thrombospondin 1 knockout null (TSP1 -/- ) mice.

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García-Posadas L, Hodges RR, Utheim TP, Olstad OK, Delcroix V, Makarenkova HP, Dartt DA