Foxo1 target genes in mouse T cells

GSE15037

Mus musculus

4 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

CD4+ and CD8+ T cells isolated from wild-type and Foxo1-deficient mice were analyzed by global gene expression profiling with Affymetrix array MOE 430 2.0. Results indicate Foxo1 regulates the expression of genes encoding positive regulators of T cell activation, differentiation, homeostasis, cell adhesion, cell migration, and cellular stress responses.

PubMed ID

19285438

Publication Title

An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.

Total Samples

Submitter’s Institution

Memorial Sloan-Kettering Cancer Center

Authors

Ouyang W, Beckett O, Flavell RA, Li MO

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-15037

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