Change in expression of genes after retinoic acid treatment of stellate cells: time course

GSE14426

Homo sapiens

30 Downloadable Samples

Illumina human-6 v2.0 expression beadchip

Submitter Supplied Information

Description

We evaluated the change in expression of genes after treatment of stellate cells with retinoic acid to understand how the stellate cells can de-differentiate and effect their physiological behaviour in pathological conditions. We then tested the changes in the gene expression in 2D and 3D culture conditions for pancreatic stellate cells and in a pancreatic cancer model.

PubMed ID

21704588

Publication Title

Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression.

Total Samples

Submitter’s Institution

Barts and the London

Authors

Froeling FE, Feig C, Chelala C, Dobson R, Mein CE, Tuveson DA, Clevers H, Hart IR, Kocher HM

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-14426

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