Gene expression levels after TMAO treatment

GSE135856

Rattus norvegicus

6 Downloadable Samples

Affymetrix Rat Clariom S Assay (clariomsrat)

Submitter Supplied Information

Description

TMAO is gut microbiota dependent metabolite catalyzed by monooxygenase FMO3 from TMA. TMAO is positively assocaited with different metabolic diseases such as diabetes, chronic kidney disease, and atherosclerosis.

PubMed ID

31543404

Publication Title

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.

Total Samples

Submitter’s Institution

boston children's hospital

Authors

Chen S, Henderson A, Petriello MC, Romano KA, Gearing M, Miao J, Schell M, Sandoval-Espinola WJ, Tao J, Sha B, Graham M, Crooke R, Kleinridders A, Balskus EP, Rey FE, Morris AJ, Biddinger SB

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-135856

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