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Accession IconGSE135670

Responses to DNA vaccine against H5 virus in spleens of Rosa 1 chickens

Organism Icon Gallus gallus
Sample Icon 13 Downloadable Samples
Technology Badge Icon Affymetrix Chicken Gene 1.1 ST Array (chigene11st)

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Description
Laying hens Rosa 1 were immunized with two doses of DNA vaccine, based on the hemagglutinin (HA) DNA from H5N1 virus, in comparison to the control group, which was administered an empty vector (pCI). Additional groups of Rosa 1 hens were treated with one dose of above described vaccine or empty vector. Gene expression changes in the spleens of chickens were investigated at 7 day post last vaccination dose.
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13
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