Aging hematopoietic progenitor/stem cells

GSE13496

Homo sapiens

29 Downloadable Samples

Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

To determine how aging impacts gene expression in hematopoietic stem cells (HSCs), human CD34+ cells from bone marrow (34BM) and mobilized stem cell products (34P38NPBSC) were examined using microarray-based expression profiling. Differential expression changes were confirmed by microarray comparisons of younger and older expanded T-cell populations.

PubMed ID

18596738

Publication Title

Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.

Total Samples

Submitter’s Institution

Fred Hutchinson Cancer Research Center

Authors

Stirewalt DL, Choi YE, Sharpless NE, Pogosova-Agadjanyan EL, Cronk MR, Yukawa M, Larson EB, Wood BL, Appelbaum FR, Radich JP, Heimfeld S

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-13496

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