Pro-BMP9 and pro-BMP10 signalling in pulmonary arterial endothelial cells

GSE134890

Homo sapiens

12 Downloadable Samples

Affymetrix Human Gene 2.1 ST Array (hugene21st)

Submitter Supplied Information

Description

This study was designed to compare the global gene expression change induced by the circulating, prodomain bound forms of BMP9 and BMP10 (pro-BMP9 and pro-BMP10) in human pulmonary arterial endothelial cells (PAECs). This is different from many previous studies which used the growth factor domain of BMP9 and/or BMP10.

PubMed ID

32238803

Publication Title

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms.

Total Samples

Submitter’s Institution

University of Cambridge

Authors

Salmon RM, Guo J, Wood JH, Tong Z, Beech JS, Lawera A, Yu M, Grainger DJ, Reckless J, Morrell NW, Li W

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-134890

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