Expression data from airway epithelial cell-conditioned monocyte-derive dendritic cells

GSE12773

Homo sapiens

10 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Dendritic cells differentiate from their precursors in the airway mucosa under local environmental instruction. Airway epithelial cells (AEC) are a potent source of both pro- and anti-inflammatory mediators and are in intimate contact with intraepithelial DC and their precursors. Thus, AEC are likely candidates for influencing this differentiation process in order to tailor the DC for optimal function in the airway mucosa.

PubMed ID

19109137

Publication Title

Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease.

Total Samples

Submitter’s Institution

Telthon Institute for Child Health Research

Authors

Rate A, Upham JW, Bosco A, McKenna KL, Holt PG

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-12773

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