Untreated 32Dcl3 cell lines expressing oncogenic tyrosine kinases or cells treated with small molecule inhibitors

GSE11794

Mus musculus

64 Downloadable Samples

Affymetrix Murine Genome U74A Version 2 Array (mgu74av2), Affymetrix Murine Genome U74A Array (mgu74a)

Submitter Supplied Information

Description

Oncogenic tyrosine kinases, such as BCR-ABL, TEL-ABL, TEL-PDGF-beta-R and FLT3-ITD, play a major role in the development of hematopoietic malignancy. They activate many of the same signal transduction pathways.

PubMed ID

18559972

Publication Title

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.

Total Samples

Submitter’s Institution

Brigham and Women's Hospital, Harvard Medical School

Authors

Tam WF, Gu TL, Chen J, Lee BH, Bullinger L, Fröhling S, Wang A, Monti S, Golub TR, Gilliland DG

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-11794

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