Gene Expression during Panobinostat Dosing

GSE109792

Homo sapiens

59 Downloadable Samples

Affymetrix Human Transcriptome Array 2.0 (hta20)

Submitter Supplied Information

Description

A clinical study evaluating the dosing of an oral HDACi panobinostat in patient infected with HIV-1. Dosing was 20 mg orally, 3 times weekly, every other week for a total of 8 weeks.

PubMed ID

29468194

Publication Title

Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits <i>Ex Vivo</i> Lipopolysaccharide-Induced Inflammatory Responses.

Total Samples

Submitter’s Institution

Aarhus University

Authors

Brinkmann CR, Højen JF, Rasmussen TA, Kjær AS, Olesen R, Denton PW, Østergaard L, Ouyang Z, Lichterfeld M, Yu X, Søgaard OS, Dinarello C, Tolstrup M

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-109792

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