Human skeletal muscle biopsies from a 3h IL-6 infusion

Skeletal muscle has been identified as a secretory organ. We hypothesized that IL-6, a cytokine secreted from skeletal muscle during exercise, could induce production of other secreted factors in skeletal muscle.

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Mortensen OH, Andersen K, Fischer C, Nielsen AR, Nielsen S, Akerström T, Aastrøm MB, Borup R, Pedersen BK