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Accession IconGSE10538

Regulation of the early embryonic RPE (retinal pigment epithelium) transcriptome by the neural retina

Organism Icon Gallus gallus
Sample Icon 22 Downloadable Samples
Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

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Purpose: The retinal pigment epithelium (RPE) forms the outer blood-retinal barrier. Primary cultures of RPE can model the barrier, but are very sensitive to culture conditions. We examined how the neural retina regulates the RPE transcriptome in a culture model of embryonic development. Attention focused on the tight junctional genes essential for barrier function.
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