Identification of target mRNAs of amyotrophic lateral sclerosis associated miR-1825 in HEK293 cells

GSE101046

Homo sapiens

3 Downloadable Samples

Affymetrix Human Gene 2.0 ST Array (hugene20st)

Submitter Supplied Information

Description

In previous studies, miR-1825 has been found to be downregulated in the serum of familial and sporadic patients with amyotrophic lateral sclerosis (ALS). In this study, we aim to identify the target mRNAs of miR-1825 using a combination of proteomic and transcriptomic approaches.

PubMed ID

30030593

Publication Title

Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS.

Total Samples

Submitter’s Institution

Ulm University

Authors

Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, Weishaupt JH

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-101046

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